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Surescripts
healthcare professionals and organizations used Clinical Direct Messaging in 20251
prescription changes made using CancelRx in 20252
of all E-Prescribing transactions augmented by Sig IQ in 20253
Provide exceptional service with expertise and efficiency
Patients seek efficient and convenient service. But tracking down information from payers and prescribers consumes precious time for pharmacists and patients. Trusted, high-quality data and seamless connectivity replace fragmented workflows—enabling stronger collaboration across the care team and faster, more confident service for patients.
Missing or messy prescription data slowing pharmacy workflows
Difficulty reaching other care providers to manage prescription changes & transfers
Limited access to clinical and benefit data
Automatically enhanced and validated data elements (such as Sigs)
Seamless connectivity between pharmacies, prescribers & payers
Workflow-embedded insights reducing manual work
Safe, clear prescriptions with less need for manual outreach
Easier, in-workflow collaboration across healthcare
More time for pharmacists to focus on patient care
New data shows how seamless prescription transfers are saving time for pharmacists and prescribers—while helping patients get medications without delay.
Evolve faster with simpler, trusted intelligence sharing
Filling prescriptions is only the beginning. Pharmacies need clear, reliable intelligence—and easier ways to share it across the care journey. With a single, trusted connection to prescribers, payers and other healthcare providers, you can access benefit and clinical insights directly within existing workflows—helping patients get the medication they need.
Intelligent prescribing
Help pharmacists confidently fill prescriptions and easily communicate with prescribers.
Interoperability
Bring pharmacists more patient insights and better communication channels.
Connect with our team to explore how we can partner to increase patient safety, reduce costs and ensure quality care.
Real-world results
Surescripts named to RxInsider’s Pharmacy500 list: Pharmacy500 recognizes organizations that meaningfully support dispensing pharmacies across the U.S. Honorees demonstrate a national presence, sustained commitment to pharmacies and active engagement with the pharmacy community.
“In order for us to drive a scalable solution, it's ‘all boats rise’ when we're able to do it for the industry versus if us at Walgreens just do it individually. Hence, why it's important for us to have partners like Surescripts.”
Expertise that supports your goals
We’ll work with you every step of the way to ensure a smooth solution implementation.
We’ll partner with you to develop powerful materials that influence resale and adoption.
We’re optimizing performance to improve prescription accuracy industrywide.
Keep pace with healthcare innovation
Find out more about how we help pharmacies
What challenges do pharmacies face that Surescripts can help address?
Pharmacists often expend valuable time tracking down patient benefit information through phone calls and faxes, which can slow prescription fulfillment, contribute to patient nonadherence and limit capacity to provide clinical care. Surescripts helps pharmacists spend more time assisting patients and less time chasing information.
How does Surescripts support pharmacy workflows?
Surescripts provides connectivity and trusted health intelligence that helps pharmacies access benefit and coverage information, communicate securely with prescribers and manage prescriptions efficiently within existing workflows.
How does Surescripts improve the prescribing process for pharmacies?
Surescripts supports clearer, safer and more efficient prescription management by standardizing e-prescribing transactions and reducing the need for manual follow-up with prescribers.
How does Surescripts help reduce administrative interactions like calls and faxes?
Secure electronic communication tools and standardized e-prescribing transactions help replace manual outreach with prescribers and payers, enabling pharmacists to focus more on patient care.
How does Surescripts support pharmacy interoperability?
Pharmacists need complete patient information and clear communication channels with other care team members in order to support coordinated care and reduce errors. With connections to 2.32 million healthcare professionals and provider organizations, Surescripts brings pharmacies a comprehensive and connected view of patient care.
- Surescripts, “2025 Annual Impact Report,” p. 22.
- Surescripts, “2025 Annual Impact Report,” p. 11.
- Surescripts, “2025 Annual Impact Report,” p. 7.