Overview
Overview

Transforming healthcare with trusted intelligence

We’re putting interoperability to work and empowering healthcare organizations across the country with the intelligence they need to optimize outcomes and operate more efficiently. Together, we are making progress toward better, safer, more cost-effective care.

Security White

Increasing patient safety

>

300

%

Quality Index Score improvement since 20161

83.9

%

of prescribers enabled to e-prescribe controlled substances2

2.7

x

improvement in successfully canceling discontinued medications with CancelRx3 

 

Dollar Sign White

Lowering costs

$

82

average savings per prescription with Real-Time Prescription Benefit4

4.83

B

care events informed by Eligibility data in 20245

40

%

lower out-of-pocket cost for high-cost drug classes6

 

Three People White

Ensuring quality care

>

416,000

clinicians locating patient records nationwide in 20247

86

%

of medication history responses augmented in 20248

271.2

M

HIPAA-compliant Clinical Direct Messages exchanged in 20249

 

Success Stories

Real-world results

Hear from others

“Sometimes it can take hours to try to get records from different places ... And so having a network that has so much information in one place is really important.”

Kristin Alvarez Director, Center for Innovation and Value

“The availability of member-specific drug cost information in the EHR points to a truly advanced prescribing experience that is helping to make medicines more accessible and affordable for consumers.”

Dr. Troyen Brennan Former Chief Medical Officer, CVS Caremark/Aetna, Parkland Health & Hospital System

“Our staff now has immediate access to each patient's benefit information. Information that used to require multiple steps and several minutes to gather now appears right away.”

Priyank Patel Owner & pharmacist, Felicity Pharmacy, Getty Square Pharmacy and Health Rx Pharmacy

“Electronic tools better align pharmacists and providers. They truly make pharmacists part of the care team.”

Dr. Nele Jessel Chief Medical Officer, athenahealth
Annual Impact Report

Tracking the impact of health intelligence sharing across the United States

In 2024, the Network Alliance exchanged more health intelligence than ever before.

View report
Unique healthcare professionals & provider organizations connected

2.29

m

+7.5% yoy

image

99.995

%

network uptime

Virtually all

insured Americans in our Master Patient Index

Health intelligence transactions exchanged

27.2

b

+14.2% yoy

health intelligence transactions exchanged

38

milliseconds

to retrieve an accurate patient match

3.58B

links to clinical document sources exchanged

Data Reports

Tracking trends & uncovering opportunities

Tap into our reports and data briefs to see how the Surescripts Network Alliance is moving the needle on some of the biggest healthcare challenges.

See all reports
.

KLAS First Look: Surescripts Interoperability Solutions

EHR vendors are improving patient outcomes using integrated communication technology.

Read KLAS research report
.

Medication Affordability & Adherence Impact Report

Access to patient-specific benefit information and out-of-pocket costs improves prescription pickup rates.

See the data
.

Specialty Obstacles & Opportunities Data Brief

Prescribers and pharmacists need help fixing missing information and treatment delays.

See survey results
.

Prescription Accuracy Impact Report

Collaboration improved e-prescription transaction accuracy by 64% from 2016 to 2019.

See the progress
.

How Are Care Teams Evolving to Fill Primary Care Gaps?

Analysis shows national and county-by-county opportunities to improve access to primary care.

Read data brief
.

Prior Authorization Fast PATH Study

High users of electronic prior authorization technology are shown to experience the greatest benefit.

Explore the benefits
White Coat Award

Honoring leaders in data accuracy and performance

The Surescripts White Coat Award celebrates leaders across the Network Alliance who are advancing prescription accuracy and performance.

See details
Bar chart LtBlue

Highest Performance

Recognizing the best overall accuracy score as measured by our data analysis engine that monitors e-prescription accuracy and pinpoints areas for improvement.

Read more
Read less
Light Bulb LtBlue

Innovation

Showcasing organizations making innovative strides toward performance optimization across the healthcare continuum—ultimately helping provide quality care in a timely manner.

Read more
Read less
E Prescribing 2 LtBlue

RxChange Champion

Highlighting organizations successfully advancing the RxChange transaction, which lets pharmacies communicate with prescribers to resolve prescription concerns within their electronic workflow.

Read more
Read less
Insights

Keep pace with healthcare innovation

See more
Footnotes:
  1. Surescripts' Quality Index Score measures the effective use of 16 key elements of electronic prescriptions, such as drug description, days supply, and potency unit code. Surescripts, “2023 National Progress Report,” p. 3.
  2. Surescripts, “2024 Annual Impact Report,” March 2025, p.8.
  3. Taylor L. Watterson et al., “CancelRx Implementation: Observed Changes to Medication Discontinuation Workflows Over Time,” Exploratory Research in Clinical and Social Pharmacy, January 25, 2022. Pharmacy cancellation rate improved from 34% to 93% after implementation.
  4. Surescripts, “2024 Annual Impact Report,” p.12.
  5. Surescripts, “2024 Annual Impact Report,” p.12.
  6. Sunita M. Desai et al., “Effects of Real-Time Prescription Benefit Recommendations on Patient Out-of-Pocket Costs,” JAMA Internal Medicine 182 (11): September 12, 2022.Surescripts, “2022 National Progress Report,” March 2023.
  7. Surescripts, “2024 Annual Impact Report,” p.19.
  8. Surescripts, “2024 Annual Impact Report,” p.20.
  9. Surescripts, “2024 Annual Impact Report,” p.19.
Read More