Transforming healthcare with trusted intelligence
We’re putting interoperability to work and empowering healthcare organizations across the country with the intelligence they need to optimize outcomes and operate more efficiently. Together, we are making progress toward better, safer, more cost-effective care.
Increasing patient safety
300
%Quality Index Score improvement since 20161
83.9
%of prescribers enabled to e-prescribe controlled substances2
2.7
ximprovement in successfully canceling discontinued medications with CancelRx3
Lowering costs
82
average savings per prescription with Real-Time Prescription Benefit4
4.83
Bcare events informed by Eligibility data in 20245
40
%lower out-of-pocket cost for high-cost drug classes6
Ensuring quality care
416,000
clinicians locating patient records nationwide in 20247
86
%of medication history responses augmented in 20248
271.2
MHIPAA-compliant Clinical Direct Messages exchanged in 20249
Real-world results
Tracking the impact of health intelligence sharing across the United States
In 2024, the Network Alliance exchanged more health intelligence than ever before.
2.29
m+7.5% yoy

99.995
%network uptime
insured Americans in our Master Patient Index
27.2
b+14.2% yoy
38
millisecondsto retrieve an accurate patient match
links to clinical document sources exchanged
DATA REPORTS
Tracking trends & uncovering opportunities
Tap into our reports and data briefs to see how the Surescripts Network Alliance is moving the needle on some of the biggest healthcare challenges.
Honoring leaders in data accuracy and performance
The Surescripts White Coat Award celebrates leaders across the Network Alliance who are advancing prescription accuracy and performance.
Highest Performance
Recognizing the best overall accuracy score as measured by our data analysis engine that monitors e-prescription accuracy and pinpoints areas for improvement.
Innovation
Showcasing organizations making innovative strides toward performance optimization across the healthcare continuum—ultimately helping provide quality care in a timely manner.
RxChange Champion
Highlighting organizations successfully advancing the RxChange transaction, which lets pharmacies communicate with prescribers to resolve prescription concerns within their electronic workflow.
Keep pace with healthcare innovation
- Surescripts' Quality Index Score measures the effective use of 16 key elements of electronic prescriptions, such as drug description, days supply, and potency unit code. Surescripts, “2023 National Progress Report,” p. 3.
- Surescripts, “2024 Annual Impact Report,” March 2025, p.8.
- Taylor L. Watterson et al., “CancelRx Implementation: Observed Changes to Medication Discontinuation Workflows Over Time,” Exploratory Research in Clinical and Social Pharmacy, January 25, 2022. Pharmacy cancellation rate improved from 34% to 93% after implementation.