With patients and the people who care for them at the center of all we do, we build connections across the healthcare industry. Together, we are the Surescripts Network Alliance.

See the impact

Making an Impact on Patients Together

We don’t exist to merely move patient data around—we’re here to serve and share the wealth of information that makes healthcare better for all.

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Increasing Patient Safety

We improved our network-wide Quality Index Score for electronic prescriptions 80% since 2016.i

Lowering costs icon

Lowering Costs

Prescribers have used Surescripts to save patients as much as $8,032 on a single prescription.ii

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Ensuring Quality Care

In 2019, we gave clinicians insight into their patients’ prior care locations more than 143 million times.iii


Reliable, Secure and Built to Scale

Every Surescripts solution—and every Surescripts Network Alliance participant—benefits from the industry-leading reliability, security and scalability of the Surescripts network.

The core building blocks of our network fall into four layers. These technologies, standards and practices make it possible to securely deliver actionable intelligence across the nation at great scale and speed.


Trust Fabric

This layer demonstrates the integrity of our system and how shared data can and cannot be used. Combined with our strong network governance, our privacy and security safeguards establish the conditions needed for interoperability to thrive.

Transport Layer

This layer makes it technologically possible to exchange electronic health information across multiple domains. Our seamless workflow integration allows healthcare professionals to safely and easily exchange standards-based transactions, access directories, match patients and locate records nationwide.

Usability Layer

Actionable patient intelligence can be delivered to the point of care within existing clinical workflows. We ensure messages can be used by receiving systems, and we orchestrate transaction steps to automate information exchange in an intelligent, secure and orderly fashion.

Optimization Layer

We proactively monitor, analyze and report on network transactions to make ongoing performance improvements that ensure actionable patient intelligence is delivered as quickly and accurately as possible. When issues arise, Surescripts technical support works to resolve them quickly.


See Who Surescripts Connects

Clinical History
(Record Locator & Exchange)

Health Systems

Technology Vendors (EHR)

Benefit Optimization
(Real Time Prescription Benefit)

Technology Vendors (EHR)

Medication History

Hospital Software


Prior Authorization

Technology Vendors (EHR)


Making an Impact Together

Learn more about the impact the Surescripts Network Alliance is having on today's most pressing healthcare issues.

Locate E-Prescribing
Pharmacies and Physicians